5-EAPB Product Description

Introduction

5-EAPB (1-(Benzofuran-5-yl)-N-ethylpropan-2-amine hydrochloride) is a synthetic entactogenic compound structurally related to amphetamines and benzofuran derivatives. It features a benzofuran ring attached to an ethylaminopropane chain, resembling the structure of 5-APB and 5-MAPB compounds known for stimulant and empathogenic effects. It is used experimentally in neuropharmacology and as a research chemical.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White crystalline solid, supplied as the hydrochloride salt.

• Purity: Typically ≥ 99% pure research-grade material.

• Solubility: Soluble in methanol, water, and polar organic solvents.

• Storage: Store in airtight containers, protected from light, refrigerated or frozen (-20°C) for stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

5-EAPB acts as an entactogen and serotonin receptor agonist with probable affinity for 5-HT2C receptors, similar to 5-APB. Its pharmacology includes potential triple monoamine reuptake inhibition affecting serotonin, dopamine, and norepinephrine neurotransmission, but precise in vivo data remain limited.

Research Applications

Used for neuropharmacological research into empathogenic and stimulant effects, receptor binding studies, and toxicity evaluation. It is important in studying novel psychoactive substances related to benzofuran amphetamines.

Safety and Handling Guidelines

Laboratory Safety

Standard laboratory precautions including gloves, lab coat, and eye protection. Handle in well-ventilated areas.

Disposal and Environmental Considerations

Dispose of chemical waste according to hazardous materials guidelines.

Regulatory Status

Considered illegal in many jurisdictions due to classification with related benzofuran amphetamines and listed in controlled substances schedules.

Frequently Asked Questions (FAQs)

1. What is 5-EAPB chemically?

• A benzofuran-entactogen amphetamine derivative.

2. What is its molecular formula and weight?

• C13H18ClNO; 239.74 g/mol.

3. What purity is standard for research?

• ≥ 99% pure.

4. How soluble is 5-EAPB?

• Soluble in methanol, water, and polar solvents.

5. Is 5-EAPB legal?

• Controlled in many countries, illegal for recreational use.

Conclusion

5-EAPB is a stable, high-purity benzofuran-based entactogenic research chemical. It serves as a key compound for studies involving serotonin receptor modulation, empathogen activity, and novel psychoactive substances.