4-Me-TMP (4-Methylmethylphenidate) Product Description

Introduction

4-Methylmethylphenidate (4-Me-TMP) is a synthetic stimulant and structural analogue of methylphenidate, commonly known for its wakefulness and alertness-promoting properties. It belongs to the class of phenethylamine derivatives and shows stimulant effects by influencing dopamine and norepinephrine systems. 4-Me-TMP has been identified as an emerging research chemical with applications in neuropharmacology and toxicology.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White crystalline solid, typically supplied as the hydrochloride salt.

• Purity: Research-grade, generally ≥ 99% purity confirmed by chromatographic and spectrometric analysis.

• Solubility: Soluble in dimethyl sulfoxide (DMSO) and other polar organic solvents.

• Storage: Store in airtight containers at -20°C, protected from light to maintain stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-Me-TMP functions as a central nervous system stimulant by modulating dopamine and norepinephrine transporters, increasing their synaptic concentration. This results in enhanced wakefulness, focus, and alertness, similar to methylphenidate but with slight structural variation affecting potency and metabolism.

Research Applications

Used in pharmacological research for studying stimulant effects, neurotoxicity, metabolic pathways, and forensic chemical identification. It has emerged recently in toxicology cases and analytical research of novel psychoactive substances.

Safety and Handling Guidelines

Laboratory Safety

Handle with standard laboratory safety gear—gloves, lab coat, eye protection—and use fume hoods in well-ventilated laboratories.

Disposal and Environmental Considerations

Dispose chemical waste in accordance with hazardous waste regulations.

Regulatory Status

Currently not explicitly controlled in many jurisdictions but may be restricted or regulated under analogue laws; for research use only.

Frequently Asked Questions (FAQs)

1. What is 4-Me-TMP chemically?

• A synthetic stimulant closely related to methylphenidate.

2. What is its molecular formula?

• C15H21NO2 · HCl (hydrochloride salt)

3. What purity is standard?

• Typically ≥ 99% for research grade.

4. What are physical properties?

• White crystalline hydrochloride salt; soluble in DMSO.

5. What is the mechanism of action?

• Dopamine and norepinephrine transporter modulation increasing synaptic levels.

6. Is it legal?

• Research chemical, legal status varies; restricted in many countries.

Conclusion

4-Methylmethylphenidate is a high-purity stimulant research chemical structurally related to methylphenidate with scientific utility in pharmacology and toxicology. Proper handling and regulation are critical for safe research use.