4-AcO-MPT Fumarate Product Description

Introduction

4-AcO-MPT fumarate is the fumaric acid salt of 4-Acetoxy-N-methyl-N-propyltryptamine (4-AcO-MPT), a synthetic psychedelic tryptamine. This compound is part of the 4-acetoxytryptamine family and acts as a prodrug to 4-HO-MPT in the body, producing psychedelic effects primarily by serotonin receptor agonism. The fumarate salt enhances chemical stability, crystallinity, and handling properties, facilitating precise dosing for research purposes.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder or solid.

• Purity: Typically ≥ 97%, verified by chromatographic and spectrometric analyses.

• Solubility: Soluble in ethanol, methanol, dimethyl sulfoxide (DMSO), and water (salt form).

• Storage Recommendations: Store in airtight, light-resistant containers in cool, dry conditions, preferably refrigerated at -20°C for long-term stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-AcO-MPT fumarate functions as a serotonin 5-HT2A receptor agonist prodrug that is metabolized to the active compound 4-HO-MPT, eliciting psychedelic effects such as altered perception, mood enhancement, and introspection. The fumarate salt form improves chemical stability and dosing consistency for research applications.

Research Applications

Used in neuropharmacological and behavioral research on psychedelic tryptamines, focusing on receptor mechanisms, metabolism, and structure-activity relationships. Also used as a reference standard in forensic toxicology.

Safety and Handling Guidelines

Laboratory Safety

Use gloves, lab coat, and eye protection while handling. Perform work in ventilated fume hoods.

Disposal and Environmental Considerations

Dispose according to hazardous waste protocols to prevent environmental contamination.

Regulatory Status

4-AcO-MPT fumarate is regulated in multiple jurisdictions and only authorized for licensed research use.

Frequently Asked Questions (FAQs)

1. What is the active metabolite of 4-AcO-MPT fumarate?

• The active compound is 4-Hydroxy-MPT (4-HO-MPT).

2. What receptors does 4-AcO-MPT affect?

• Primarily serotonin 5-HT2A receptors.

3. What is the typical purity of 4-AcO-MPT fumarate?

• Approximately ≥ 97%.

4. How should 4-AcO-MPT fumarate be stored?

• Store refrigerated at -20°C, in airtight, light-protective containers.

5. Is 4-AcO-MPT fumarate legal?

• Usage is restricted to scientific research in controlled environments.

Conclusion

4-AcO-MPT fumarate is a high-purity, fumaric acid salt form of a psychedelic tryptamine prodrug used in neuropharmacological research. Its stable salt form allows reliable dosing and handling for advanced studies into serotonin receptor-mediated psychedelic mechanisms.