4-HO-MiPT Fumarate Product Description

Introduction

4-Hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MiPT) fumarate is the fumaric acid salt of 4-HO-MiPT, a synthetic psychedelic tryptamine related structurally to psilocin. It induces serotonergic psychedelic effects, including visual enhancement, alterations of perception, and changes in cognition. The fumarate salt enhances stability and crystallinity, supporting reliable dosing and experimental reproducibility in scientific research.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White crystalline powder, often supplied as the monohydrate fumarate salt.

• Purity: ≥ 99% pure research-grade, confirmed through advanced chromatographic and spectrometric methods.

• Solubility: Soluble in dimethylformamide (30 mg/mL), DMSO (30 mg/mL), ethanol (0.5 mg/mL), and phosphate buffered saline (pH 7.2) (0.5 mg/mL).

• Boiling Point: Approximately 407.4±35.0 °C (predicted).

• Density: ~1.123 ± 0.06 g/cm3 (predicted).

• pKa: Approximately 10.08±0.40 (predicted).

• Storage: Store in airtight, light-protected containers at –20 °C for optimal chemical stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-HO-MiPT fumarate acts as a potent agonist at serotonin 5-HT2A receptors, eliciting psychedelic effects typical of 4-hydroxytryptamines, such as enhanced sensory perception, visual hallucinations, and time distortion. The amine substitutions influence pharmacokinetics and subjective effects.

Research Applications

Commonly employed for pharmacological, neurobehavioral, and forensic research investigating the structure-activity relationships and mechanisms of psychedelic tryptamines. Its well-characterized fumarate salt form facilitates consistent scientific research and dosing accuracy.

Safety and Handling Guidelines

Laboratory Safety

Standard protected handling including gloves, lab coat, and eye protection is recommended. Work in well-ventilated or fume hood environments.

Disposal and Environmental Considerations

Dispose of according to hazardous chemical waste protocols compliant with local regulations.

Regulatory Status

Controlled substance status varies by jurisdiction; restricted to licensed scientific research only.

Frequently Asked Questions (FAQs)

1. What is the chemical nature of 4-HO-MiPT fumarate?

• It is the fumarate salt monohydrate of 4-Hydroxy-N-methyl-N-isopropyltryptamine.

2. Which receptors does it affect?

• Primarily the serotonin 5-HT2A receptor.

3. What purity is guaranteed?

• Highly pure, ≥ 99% for research use.

4. How soluble is 4-HO-MiPT fumarate?

• Soluble in DMF, DMSO, ethanol, and buffers to varying degrees.

5. How should it be stored?

• In airtight, light-protected conditions, refrigerated at -20°C.

Conclusion

4-HO-MiPT fumarate is a high-purity, chemically stable psychedelic tryptamine fumarate salt used in advanced research to study serotonergic psychedelic effects. Reliable reproducibility, combined with comprehensive physico-chemical documentation, supports its utility in pharmacological and behavioral studies.