Buy 4-AcO-DMT (O-Acetylpsilocin) – USA & Europe

1. What is 4-AcO-DMT?

4-AcO-DMT, also known as O-Acetylpsilocin or psilacetin, is a synthetic psychedelic tryptamine that acts as a prodrug to psilocin, the active compound in magic mushrooms. It is used in research to explore serotonin receptor-mediated psychedelic effects and neuropharmacology. 4-AcO-DMT is structurally similar to psilocin but with an acetyl group increasing its stability and making it easier to handle in lab settings.

2. Chemical Composition & Structure of 4-AcO-DMT

The chemical formula is C1414H1818N22O22 with a molar mass of 246.3 g/mol. It is an acetylated derivative of psilocin, featuring an acetoxy group on the 4-position of the indole ring. Commonly available as the fumarate salt or free base, it forms an off-white to pale beige solid with good stability under controlled storage.

3. Research Applications of 4-AcO-DMT

Used widely in neuropharmacological and biochemical research, 4-AcO-DMT functions as a tool to study 5-HT2A receptor activation and psychedelic mechanisms. It serves as a prodrug that metabolizes to psilocin in biological systems, assisting in the investigation of psychedelic effects, receptor binding, and pharmacodynamics akin to psilocybin.

4. Recommended Laboratory Handling & Safety Guidelines

Handle in a ventilated fume hood with gloves and eye protection. Prevent skin or eye contact and avoid inhalation of powders. Store securely, maintain proper labeling, and use precise measurement tools.

5. Hazard Warnings & Risk Statements (GHS Classification If Applicable)

4-AcO-DMT should be treated as a hazardous chemical with potential irritation and toxicity risks. Avoid ingestion or direct skin and eye contact. Standard chemical safety practices apply.

6. Compatibility with Other Reagents or Substances

Compatible with organic solvents like methanol and ethanol. Avoid strong acids, bases, and oxidizing agents which may hydrolyze the acetyl group and degrade the compound.

7. Emergency Protocols for Accidental Exposure

• Wash skin or eyes thoroughly with water for 15 minutes if contact occurs.

• Move exposed individuals to fresh air if inhalation occurs.

• Seek immediate medical advice if ingested or if severe symptoms manifest.

8. Storage Stability & Shelf Life Monitoring

Store in airtight, amber containers at -20°C or refrigerated (2–8°C) to minimize degradation. Avoid moisture and prolonged light exposure. Stability extends for years under optimal conditions.

9. Can Researchers Purchase 4-AcO-DMT Without a License?

Yes, purchase for laboratory research is permitted; nonetheless, confirming local legal standing before procurement is the buyer’s responsibility.

10. Is It Legal to Order 4-AcO-DMT Online in My Country?

Legal status varies globally; many countries regulate or prohibit 4-AcO-DMT under analog or scheduled substance laws. Proper legal review must be conducted.

11. Is 4-AcO-DMT Considered Safe for Laboratory Use?

Safe if handled in accordance with established chemical safety guidelines. It is intended strictly for research, with no approved human consumption.

12. Special Considerations for Researchers with Medical Conditions

Avoid handling by individuals with psychiatric or cardiovascular vulnerabilities due to the compound’s potent serotonergic activity.

13. Allergen Exposure Risks When Handling 4-AcO-DMT

No specific allergenic data; use PPE to prevent any contact-related sensitization or irritation.

14. Can 4-AcO-DMT Be Used in Combination with Other Research Materials?

Compatible with typical solvents and reagents used in serotonin receptor study protocols. Check compatibility before mixing with potent oxidizers or acids.

15. Can Pregnant Researchers Handle 4-AcO-DMT?

Not recommended due to insufficient safety data.

16. Proper Handling Protocols for Best Experimental Consistency

Use high-precision measurement tools; limit sample exposure to air and light; store aliquots for experimental reproducibility.

17. Optimizing Research Output with 4-AcO-DMT

Maintain solvent purity, avoid freeze-thaw cycles, and carefully document batch data for consistency in results.

18. Reported Results and Efficacy in Experimental Settings

4-AcO-DMT produces serotonergic effects closely mirroring psilocin, effective in receptor binding studies and behavioral pharmacology.

19. Known Adverse Reactions or Lab Incidents

No widespread lab incidents reported, but caution advised given psychoactive potential and chemical reactivity.

20. What To Do in Case of Severe Exposure or Contamination

Decontaminate immediately and seek emergency medical assistance, providing chemical identity and handling data to responders.

21. Can Alcohol-Based Solvents Be Used with 4-AcO-DMT?

Yes, methanol and ethanol are suitable solvents for formulation and testing purposes.

22. What If I Skip a Scheduled Measurement or Test Cycle?

Dispose of potentially unstable solutions and prepare fresh batches before continuing assays.

23. Maximum Recommended Duration of Experimental Storage or Use

Solid form is stable for years in proper storage; solutions ideally used within 1–3 months.

24. Stability After Discontinuation of Testing

Degrades slowly upon repeated exposure to air, moisture, and light; store carefully and monitor sample conditions.

25. Is There Risk of Dependency or Sensitization?

No known risk of physical dependency. Use PPE to avoid dermal sensitization.

26. Long-Term Storage Recommendations for 4-AcO-DMT

Store in airtight, opaque containers at refrigerated temperatures (2–8°C), protected from moisture.

27. Alternative Research Chemicals with Similar Properties

• Psilocin (4-HO-DMT)

• Psilocybin (4-PO-DMT)

• 4-HO-MiPT (hydroxy-substituted tryptamine)