4-HO-DPT Fumarate Product Description

Introduction

4-Hydroxy-N,N-di-n-propyltryptamine (4-HO-DPT) fumarate is the fumaric acid salt form of 4-HO-DPT, a synthetic psychedelic tryptamine structurally related to psilocin. This compound is noted for its psychedelic effects and is used primarily in neuropharmacological research. The fumarate salt enhances chemical stability, crystalline structure, and handling properties essential for precise dosing and experimental reproducibility.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: Off-white to white crystalline solid or powder, often as a tetrahydrate.

• Purity: Typically ≥ 97%, confirmed via chromatography and spectroscopy.

• Solubility: Soluble in water and polar solvents such as methanol, ethanol, DMSO.

• Storage Recommendations: Store in airtight, light-protected, and cool conditions, preferably refrigerated or frozen to preserve quality.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-HO-DPT fumarate acts as an agonist at serotonin 5-HT2A receptors, eliciting psychedelic effects by modulating neural signaling associated with perception, mood, and cognition. Its structural similarity to psilocin supports its activity profile as a classic tryptamine psychedelic.

Research Applications

Used in experimental and preclinical neuropharmacology to study psychedelic mechanisms, receptor binding, behavioral pharmacology, and metabolism. The fumarate salt ensures improved handling, reproducibility, and chemical stability for scientific research.

Safety and Handling Guidelines

Laboratory Safety

Use with gloves, lab coat, and eye protection. Conduct manipulations in ventilated fume hoods or well-aerated spaces.

Disposal and Environmental Considerations

Dispose residual chemical waste following hazardous chemical regulations to minimize environmental impact.

Regulatory Status

4-HO-DPT fumarate is regulated in several jurisdictions and restricted to authorized research uses.

Frequently Asked Questions (FAQs)

1. What is 4-HO-DPT fumarate?

• The fumarate salt of 4-Hydroxy-N,N-di-n-propyltryptamine, a psychedelic tryptamine.

2. What receptors does it primarily affect?

• Serotonin 5-HT2A receptor agonist.

3. What purity standards are common?

• ≥ 97% purity for research-grade.

4. How should it be stored?

• Airtight, light-protected containers refrigerated or frozen.

5. Is it legal?

• Regulated and limited to licensed scientific research.

Conclusion

4-HO-DPT fumarate is a high-purity, chemically stable crystalline salt used extensively in controlled psychedelic research. It facilitates reproducible studies on serotonin receptor activity and psychedelic effects with enhanced handling and formulation benefits.