4-HO-EPT Fumarate Product Description

Introduction

4-HO-EPT fumarate is the fumaric acid salt form of 4-Hydroxy-N-ethyl-N-propyltryptamine (4-HO-EPT), a synthetic psychedelic tryptamine. It features a hydroxy group at the 4-position of the indole ring and dual alkyl substitutions (ethyl and propyl) on the amine group, which influence its receptor binding and pharmacokinetics. 4-HO-EPT belongs to the family of 4-hydroxy-tryptamines, related to psilocin and other psychedelic compounds. The fumarate salt enhances chemical stability and crystallinity, enabling precise dosing and long-term storage.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: Off-white crystalline or powder solid, often in a hygroscopic fumarate salt form.

• Purity: Typically ≥ 97%, confirmed by chromatographic and spectrometric analysis.

• Solubility: Soluble in polar solvents such as water, methanol, ethanol, and DMSO.

• Storage: Store in airtight, light-shielded containers under cool, dry conditions, preferably refrigerated or frozen (-20°C) to preserve stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-HO-EPT fumarate is a serotonin 5-HT2A receptor agonist, producing psychedelic effects through modulation of serotoninergic neural pathways. The presence of ethyl and propyl groups influences receptor affinity and pharmacokinetic properties, differentiating it from analogs like psilocin.

Research Applications

Widely used for neuropharmacological research to understand psychedelic receptor activity, behavioral effects, and metabolism. The fumarate salt form ensures consistent dosing and improved handling in laboratory conditions.

Safety and Handling Guidelines

Laboratory Safety

Standard precautions include use of gloves, lab coats, and eye protection. Work in ventilated areas or fume hoods to minimize exposure.

Disposal and Environmental Considerations

Dispose of waste materials responsibly according to hazardous chemical regulations.

Regulatory Status

Controlled as a research chemical, 4-HO-EPT fumarate is restricted for use in licensed scientific investigations.

Frequently Asked Questions (FAQs)

1. What is 4-HO-EPT fumarate chemically?

• A 4-hydroxytryptamine psychedelic with ethyl and propyl amine substitutions, in fumarate salt form.

2. What receptors does it target primarily?

• Serotonin 5-HT2A receptors.

3. What purity can be expected?

• Research-grade purity is ≥ 97%.

4. How to store 4-HO-EPT fumarate?

• Airtight, light-protected environment; refrigeration/freeze recommended.

5. Is it a legal compound?

• Regulated and limited to scientific research applications.

Conclusion

4-HO-EPT fumarate is a high-purity, chemically stable psychedelic tryptamine salt used in neuropharmacological and behavioral research. It enables thorough exploration of serotonergic psychedelic mechanisms with enhanced stability and handling properties.