4-HO-MET Fumarate Product Description

Introduction

4-Hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET) fumarate is a synthetic psychedelic tryptamine closely related structurally to psilocin, the active component of psilocybin mushrooms. Known also by the name metocin, 4-HO-MET produces classical psychedelic effects through serotonin receptor agonism, primarily interacting with 5-HT2A receptors. The fumarate salt form offers enhanced stability and crystallinity, suited for precise dosing and scientific research use.

Chemical Properties and Specifications

Structural and Molecular Characteristics

Physical Properties and Purity Standards

• Appearance: White to off-white crystalline powder or pellets.

• Purity: 99% pure (research-grade), validated via chromatographic and spectrometric methods.

• Solubility: Soluble in polar solvents like ethanol, methanol, DMSO, and moderately soluble in water.

• Storage: Store in airtight, light-protected containers under refrigerated or frozen (-20°C) conditions to maintain stability.

Pharmacological Profile and Mechanism of Action

Mechanism of Action

4-HO-MET fumarate acts as a potent agonist at serotonin 5-HT2A receptors, producing psychedelic effects including altered sensory perception, mood enhancement, and introspection. Its structure closely resembles psilocin, implying similar pharmacodynamics.

Research Applications

Widely used in neuropharmacological and behavioral research on psychedelics, receptor binding studies, and metabolism investigations. Its fumarate salt form ensures dosing consistency and chemical stability for reliable scientific experiments.

Safety and Handling Guidelines

Laboratory Safety

Use personal protective equipment such as gloves, lab coats, and eye protection. Handle in ventilated areas or fume hoods.

Disposal and Environmental Considerations

Follow hazardous chemical waste disposal regulations.

Regulatory Status

4-HO-MET fumarate is controlled in several jurisdictions and licensed exclusively for authorized research use.

Frequently Asked Questions (FAQs)

1. What is 4-HO-MET fumarate?

• Fumarate salt of 4-Hydroxy-N-methyl-N-ethyltryptamine, a psychedelic tryptamine.

2. What receptors are targeted?

• Predominantly serotonin 5-HT2A receptors.

3. What purity is standard?

• 99% pure, research-grade.

4. How should it be stored?

• Airtight, light-protected, refrigerated/frozen.

5. Is it legal for general use?

• No, restricted to licensed scientific research.

Conclusion

4-HO-MET fumarate is a chemically stable, high-purity psychedelic research chemical valuable for studies involving serotonergic psychedelics. The fumarate salt offers reproducibility and enhanced stability for rigorous scientific investigation.