1D-LSD 225 MCG Pellets Product Description

Introduction

1D-LSD is a novel research chemical and semi-synthetic lysergamide structurally related to LSD, featuring a dimethylcyclobutane-1-carbonyl group attached at the nitrogen-1 position of the lysergic acid moiety. Delivered as 225 microgram pellets, this form facilitates precise dosing for scientific studies investigating psychedelic neuropharmacology and serotonin receptor interactions. The structural modification distinguishes 1D-LSD from classical LSD and other N1-substituted derivatives, allowing comprehensive research into its pharmacology and metabolism.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Formula: C27H35N3O2

• Molecular Weight: Approximately 433.55 g/mol

• CAS Number: Not widely assigned (research chemical status)

• IUPAC Name: (8β)-1-(1,2-dimethylcyclobutane-1-carbonyl)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide

• Synonyms: 1D-LSD, 1-(1,2-dimethylcyclobutane-1-carbonyl)-LSD

Physical Properties and Purity Standards

• Appearance: Solid pellets containing precise doses of 225 micrograms of the compound each. The raw molecule is a crystalline powder before pellet preparation.

• Purity: Purity typically ≥ 98%, consistent with research-grade requirements.

• Solubility: Soluble in organic solvents such as ethanol, methanol, and acetonitrile; minimal water solubility.

• Storage Recommendations: Recommended to store in airtight, light-resistant containers under cool, dry conditions to maintain stability and potency, ideally refrigerated.

Pharmacological Profile and Mechanism of Action

Proposed Mechanism of Action

1D-LSD acts principally as an agonist of serotonin 5-HT2A receptors, the primary molecular targets mediating psychedelic effects. It is believed to act as a prodrug, enzymatically metabolizing in vivo to LSD, which then exerts classic hallucinogenic effects through serotonergic pathways. Preclinical models indicate analogous behavioral and pharmacodynamic profiles to LSD with differing potency and duration.

Research Applications

Prepared pellets enable accurate dose administration for receptor binding studies, metabolic profiling, and functional assays of psychedelic ligands. 1D-LSD’s unique chemical structure supports investigations into structure-activity relationships and pharmacokinetic variations among lysergamide analogs.

Comparative Analysis with Related Compounds

Comparison with Related Compounds

1D-LSD’s defining dimethylcyclobutane-1-carbonyl moiety differs from other N1 acyl substitutions such as butanoyl (1B-LSD) or propionyl (1P-LSD) groups, affecting pharmacological properties uniquely. It bears structural similarity to LSD but confers distinct metabolic and receptor engagement features, enriching comparative research.

Advantages for Research

The pellet format facilitates precise and reproducible microdose administration, essential for studies on subtle psychedelic effects. 1D-LSD’s distinct molecular profile expands the toolkit for probing receptor pharmacology and prodrug mechanics within psychedelic research.

Safety and Handling Guidelines

Laboratory Safety

Engage standard protective measures: gloves, lab coat, and eye protection. Handle in properly ventilated conditions to avoid inhalation or contact. Maintain cleanliness and avoid contamination.

Disposal and Environmental Considerations

Dispose of waste substances according to hazardous chemical regulations. Prevent environment contamination through controlled disposal and chemical neutralization when necessary.

Regulatory Status

1D-LSD is classified as a controlled research chemical analogue in many jurisdictions. It is restricted to scientific research use and is not approved for human consumption.

Frequently Asked Questions (FAQs)

1. What is the typical dose for 1D-LSD pellets?

• Pellets hold 225 micrograms each, permitting precise experimental dosing.

2. How pure is the research-grade 1D-LSD?

• Generally over 98% purity.

3. Does 1D-LSD metabolize to LSD?

• Yes, it is believed to act as a prodrug metabolizing into LSD.

4. What solvents can dissolve 1D-LSD pellets?

• Organic solvents such as ethanol, methanol, and acetonitrile.

5. Is 1D-LSD legal?

• It is legally restricted and only authorized for laboratory research in most regions.

Conclusion

1D-LSD 225 MCG Pellets represent a high-purity, structurally unique LSD analog provided in a precise microdose pellet form. They allow accurate dosing and are vital for research into psychedelic pharmacology, receptor binding, and prodrug metabolism in controlled scientific environments.