2-FMA 30 MG Pellets (2-Fluoromethamphetamine) Product Description

Introduction

2-FMA (2-Fluoromethamphetamine) is a synthetic stimulant belonging to the amphetamine class, characterized by a fluorine atom substituted at the second position of the phenyl ring and a methyl group attached to the amine nitrogen. Presented as 30 milligram pellets, 2-FMA is primarily intended for research purposes to evaluate stimulant pharmacology, neurochemical effects, and structure-activity relationships. It is a potent central nervous system stimulant with effects on dopamine, norepinephrine, and serotonin neurotransmission.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Formula: C10H14FN

• Molecular Weight: 167.22 g/mol

• CAS Number: 1780004-19-4

• IUPAC Name: 1-(2-fluorophenyl)-N-methylpropan-2-amine

• Synonyms: 2-Fluoromethamphetamine, 2-FMA, 2-FMAP

Physical Properties and Purity Standards

• Appearance: Typically white to off-white small pellets or tablets containing 30 mg of 2-FMA each.

• Purity: Research-grade purity usually ≥ 97%.

• Solubility: Soluble in organic solvents including ethanol, methanol, DMSO, and moderately soluble in water.

• Storage Recommendations: Store in airtight containers at temperatures below -20°C, away from moisture and light to maintain stability.

Pharmacological Profile and Mechanism of Action

Proposed Mechanism of Action

2-FMA acts by promoting the release and inhibiting the reuptake of dopamine, norepinephrine, and serotonin in the central nervous system, leading to enhanced stimulant effects. The fluorine substitution modifies its lipophilicity and metabolic profile, influencing potency and duration compared to methamphetamine.

Research Applications

Used in laboratory research for studying stimulant pharmacodynamics, neurochemical effects, and receptor interactions of substituted amphetamines. 2-FMA pellets facilitate precise dosing for behavioral and biochemical experiments exploring the effects of fluorinated stimulants.

Comparative Analysis with Related Compounds

Comparison with Related Compounds

2-FMA is closely related to methamphetamine but contains a fluorine atom at position 2 of the phenyl ring, and differs from 2-FA (2-fluoroamphetamine) by the additional methyl group on the amine nitrogen. Compared to 3- and 4-FMA positional isomers, 2-FMA shows unique stimulant properties and effects.

Advantages for Research

The pellet format allows reproducible, controlled dosing suitable for preclinical and pharmacological research. 2-FMA’s modified chemical structure enables detailed studies on the impact of fluorine substitution on stimulant effects and metabolism.

Safety and Handling Guidelines

Laboratory Safety

Handle with gloves, lab coat, and eye protection in well-ventilated or fume hood environments to avoid exposure by inhalation or skin contact.

Disposal and Environmental Considerations

Disposal must comply with hazardous waste regulations. Avoid environmental contamination via proper containment and neutralization.

Regulatory Status

2-FMA is regulated as a controlled substance analog in many jurisdictions and is permitted only for licensed scientific research.

Frequently Asked Questions (FAQs)

1. What are the typical uses of 2-FMA in research?

• Studying stimulant pharmacology, neurotransmitter release, and CNS effects.

2. How does 2-FMA differ chemically from methamphetamine?

• Presence of a fluorine atom at position 2 on the phenyl ring and a methyl group on the amine nitrogen.

3. How should 2-FMA pellets be stored?

• Airtight containers below -20°C, protected from light and moisture.

4. What solvents dissolve 2-FMA?

• Ethanol, methanol, DMSO, and moderately soluble in water.

5. Is 2-FMA legal?

• It is legally controlled and restricted to licensed research environments.

Conclusion

2-FMA 30 MG Pellets provide a research-grade, fluorinated methamphetamine analog in a convenient pellet form for study of stimulant pharmacology and neurochemical effects. Its chemical modifications allow investigation into dopaminergic and serotonergic systems under regulated laboratory conditions.