Chem-mist 4-HO-MET Spray 7%

PRODUCT DESCRIPTION

Introduction

Chem-mist 4-HO-MET Spray 7% is a liquid formulation of 4-Hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET), a psychedelic tryptamine analog structurally related to psilocin, the active component in psychedelic mushrooms. This 7% solution is designed for sublingual delivery, providing precise dosing and rapid onset of psychoactive effects suitable for psychopharmacological research into serotonergic psychedelic compounds.

Chemical Properties and Specifications

2.1 Structural and Molecular Characteristics

• Chemical Name: 4-Hydroxy-N-methyl-N-ethyltryptamine

• Chemical Formula: C13H18N2O

• Molecular Weight: 218.29 g/mol

• CAS Number: 77872-41-4

• IUPAC Name: 3-[2-(ethyl(methyl)amino)ethyl]-1H-indol-4-ol

• Synonyms:

  • 4-HO-MET

  • 4-Hydroxy-MET

  • Metocin

  • Methylcybin

2.2 Physical Properties and Purity Standards

• Appearance: Clear to light beige liquid solution with slight opalescence

• Concentration: 7% w/v (70 mg/mL approx)

• Purity: ≥98% pharmaceutical-grade purity

• Solubility: Soluble in organic solvents like ethanol and DMSO, compatible with aqueous solvent mixtures for spray formulations

• Storage Recommendations: Store in amber bottle at 4°C to -20°C, sealed and protected from light and moisture to preserve stability

Pharmacological Profile and Mechanism of Action

3.1 Mechanism of Action

4-HO-MET acts primarily as an agonist at serotonin 5-HT2A receptors, eliciting psychedelic effects consistent with tryptamine hallucinogens such as psilocin. It induces perceptual, emotional, and cognitive alterations mediated by serotonergic neurotransmission.

3.2 Research Applications

The spray formulation facilitates consistent dosing and rapid absorption, making it suitable for psychopharmacological, behavioral, and metabolic studies investigating psychedelic tryptamines. The 7% concentration allows flexible titration for dose-response research.

Comparative Analysis with Related Compounds

4.1 Compared to Psilocin and Other Analogues

4-HO-MET shares structural and pharmacological similarities with psilocin and 4-HO-DET but has a methyl-ethyl substitution that influences potency and pharmacokinetics. Spray form offers advantages over blotter or capsule forms in absorption and dosing precision.

4.2 Research Advantages

The chemical stability, high purity, and liquid formulation support reproducible experimental results and simplified administration routes for in vivo studies.

Safety and Handling Guidelines

5.1 Laboratory Safety

Use standard PPE including gloves and safety glasses. Handle in well-ventilated areas and avoid direct skin contact or inhalation.

5.2 Disposal

Dispose of per hazardous chemical waste guidelines to prevent contamination.

5.3 Regulatory Status

4-HO-MET is regulated or controlled in several jurisdictions due to its psychoactive properties. Verify local laws before handling or use.

Frequently Asked Questions (FAQs)

1. What is the active compound in Chem-mist 4-HO-MET spray?
   4-Hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET).

2. What concentration is the spray solution?
   7% w/v, approximately 70 mg/mL.

3. How is the spray administered?
   Sublingual inhalation for rapid absorption.

4. What effects does 4-HO-MET produce?
   Psychedelic effects akin to psilocin including sensory distortion and altered cognition.

5. Is 4-HO-MET legal?
   It is regulated in multiple countries; always verify before use.

Conclusion

Chem-mist 4-HO-MET Spray 7% is a high-purity, liquid psychedelic research chemical ideal for accurate dosing and rapid sublingual delivery. It supports detailed serotonergic psychopharmacology research under strict safety and regulatory compliance.