Methallylescaline Hydrochloride (MAL HCl) Product Description

Introduction

Methallylescaline hydrochloride is the hydrochloride salt form of Methallylescaline (MAL), a psychedelic phenethylamine and structural analog of mescaline. It is characterized by its potent hallucinogenic effects, believed to act primarily as a serotonin 5-HT2A receptor agonist. MAL hydrochloride is used in pharmacological and forensic research, offering a stable and soluble form ideal for laboratory studies.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Name: 4-Methylallyloxy-3,5-dimethoxyphenethylamine hydrochloride

• Molecular Formula: C14H21NO3 · HCl

• Molecular Weight: 287.78 g/mol

• CAS Number: 207740-41-8

• IUPAC Name: 3,5-dimethoxy-4-[(2-methyl-2-propen-1-yl)oxy]phenethylamine hydrochloride

Physical and Chemical Properties

• Appearance: White crystalline powder

• Solubility: Soluble in DMSO and ethanol at ≥10 mg/mL, soluble in PBS (pH 7.2) at similar concentrations

• Stability: Store at -20°C; avoid repeated freeze-thaw cycles and protect from light and moisture

• Storage: Stable for up to 1 month at -20°C in solution, up to 6 months at -80°C

Pharmacological Profile and Mechanism of Action

• Acts as a potent agonist of serotonin 5-HT2A receptors, eliciting psychedelic effects similar to mescaline and related compounds

• Exhibits a steep dose-response curve with hallucinogenic duration lasting 12-16 hours

• Effects include altered sensory perception, mood elevation, and cognitive changes

Research Applications

• Used in psychopharmacology to investigate serotonergic psychedelics

• Forensic studies utilize MAL HCl for substance identification

• Analytical chemistry for developing LSD- and mescaline-analog detection methods

Safety and Handling

• Wear appropriate PPE including gloves, lab coat, and eye protection

• Use in well-ventilated lab spaces or fume hoods

• Avoid inhalation, ingestion, and skin contact

• Dispose of chemical waste per hazardous materials guidelines

Regulatory Status

• Research chemical for laboratory use only

• Not approved for human consumption or medical use

• Subject to analogue controlled substance laws in some jurisdictions

Frequently Asked Questions (FAQs)

1. What is Methallylescaline hydrochloride?
   The hydrochloride salt form of the psychedelic compound Methallylescaline (MAL).

2. What is its molecular weight?
   287.78 g/mol.

3. How is it typically stored?
   At -20°C or colder, protected from light and moisture.

4. What receptors does it target?
   Primarily serotonin 5-HT2A receptors.

5. What is the half-life or duration of effects?
   Effects last approximately 12 to 16 hours.

Conclusion

Methallylescaline hydrochloride is a stable, research-grade psychedelic phenethylamine specific for advanced psychopharmacology and analytical forensic studies. Its consistent purity and solubility make it highly suitable for laboratory use under controlled conditions.