MK-677 (Ibutamoren) 10 mg Pellets Product Description

Introduction

MK-677, also known as Ibutamoren, is a potent, orally active, non-peptide growth hormone secretagogue (GHS) that mimics the action of ghrelin by binding to the ghrelin receptor (GHSR). This property stimulates the release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) without increasing cortisol levels, making it a popular compound for research into hormone regulation, muscle growth, metabolic health, and anti-aging. MK-677 10 mg pellets offer precise dosing suitable for laboratory and preclinical research.

Chemical Properties and Specifications

Structural and Molecular Characteristics

• Chemical Name: Ibutamoren mesylate (MK-677)

• Molecular Formula: C28H40N4O8S2 (Mesylate salt)

• Molecular Weight: 624.77 g/mol (mesylate salt)

• CAS Number: 159752-10-0

• Synonyms: MK-0677, Ibutamoren, Nutrobal, MK677

Physical Form and Composition

• Form: Solid pellets

• Dosage: 10 mg of MK-677 per pellet

• Appearance: White to light beige solid powder formed into pellets

• Solubility: Water soluble up to 5 mg/mL; soluble in DMSO and ethanol

• Storage: Store at 2-8°C for powder; -20°C recommended for long-term storage of solutions; protect from moisture and light

Pharmacological Profile and Mechanism of Action

• MK-677 activates the ghrelin receptor (growth hormone secretagogue receptor) to stimulate GH and IGF-1 secretion

• Effects include increased muscle mass, bone density, improved metabolism, and potential anti-aging benefits

• Does not suppress natural growth hormone secretion – promotes more physiologic pulsatile secretion

Research Applications

• Studies of endocrine function, GH regulation, and metabolic disorders

• Research on muscle wasting, osteoporosis, and aging-related decline

• Exploration of potential therapeutic applications in GH deficiency and sarcopenia

Safety and Handling

• Use standard lab PPE including gloves, goggles, and lab coat

• Handle in well-ventilated areas, avoid dust and inhalation

• Store securely in airtight containers to avoid moisture contamination

Regulatory Status

• Research chemical only; not approved for human therapeutic use

• Controlled under specific regulatory contexts; check local laws

Frequently Asked Questions (FAQs)

1. What is MK-677?
   A non-peptide growth hormone secretagogue (Ibutamoren).

2. What dose is in each pellet?
   10 mg of MK-677 per pellet.

3. How does MK-677 work?
   It activates ghrelin receptors to increase GH and IGF-1 secretion.

4. What are common research uses?
   Endocrine studies, muscle wasting, bone health, and aging.

5. How should MK-677 pellets be stored?
   Between 2-8°C; protect from moisture and light.

Conclusion

MK-677 (Ibutamoren) 10 mg pellets provide a precise, stable form of a potent growth hormone secretagogue for research into GH and IGF-1 endocrine regulation, metabolic health, and age-related conditions.