Salvinorin A
$60.00
Salvinorin A is a potent naturally occurring hallucinogen from Salvia divinorum acting as a selective kappa-opioid receptor agonist, researched for its unique psychoactive and therapeutic potential.
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1. What is Salvinorin A?
Salvinorin A is a potent, naturally occurring hallucinogenic compound classified as a trans-neoclerodane diterpenoid. It is the primary active constituent of the plant Salvia divinorum, known for its unique dissociative and hallucinogenic effects. Unlike classical psychedelics, Salvinorin A does not act on serotonin receptors but is a powerful agonist of the kappa-opioid receptor (KOR).
2. Chemical Composition & Structure
The molecular formula of Salvinorin A is C23H28O8, with a molecular weight of approximately 432.46 g/mol. It is a non-nitrogenous compound, distinct from alkaloids, and lacks ionizable groups. Its structure includes multiple oxygen-containing functional groups and several chiral centers, contributing to its biological activity.
3. Research Applications
Salvinorin A is studied extensively for its unique KOR agonist activity and its implications in neuropharmacology. Research explores its potential in modulating pain, mood disorders, addiction, and its distinctive hallucinogenic mechanism differing from classical serotonergic psychedelics.
4. Recommended Laboratory Handling & Safety Guidelines
Handle with appropriate gloves and avoid inhalation or ingestion. Store in airtight containers away from light and moisture to maintain compound stability. Use in well-ventilated areas following institutional safety protocols.
5. Hazard Warnings & Risk Statements
Salvinorin A is a potent psychoactive substance and should be handled cautiously to prevent unintended effects. Proper labeling and safety measures are mandatory.
6. Compatibility with Other Substances
Limited data; avoid mixing with other CNS-active drugs unless under controlled study to prevent unexpected pharmacodynamic interactions.
7. Emergency Protocols for Exposure
In case of accidental ingestion or strong adverse psychological reactions, provide supportive care and seek medical assistance.
8. Storage Stability & Shelf Life
Salvinorin A is stable in crystalline form but has poor solubility in water limiting formulation options. Store in dry, dark, and cool conditions for extended shelf life.
9. Licensing & Purchase
Available for research purposes; verify legal status before purchase as it is regulated in various jurisdictions.
10. Legal Status for Online Purchase
Varies by country; ensure compliance with local laws.
11. Laboratory Safety Measures
Use protective equipment and adhere to chemical safety standards.
12. Medical Considerations
Avoid use in individuals with psychiatric vulnerabilities.
13. Allergen Risks
Minimal; gloves recommended.
14. Interactions with Other Chemicals
Caution with concurrent CNS agents.
15. Pregnancy Precautions
Not advised due to lack of safety data.
16. Handling Consistency for Research
Use precise dosing due to high potency; maintain detailed records.
17. Optimizing Research Outcomes
Use high-purity compounds; control environmental conditions.
18. Reported Pharmacological Effects
Produces potent kappa-opioid receptor agonism leading to intense dissociative and hallucinogenic experiences with distinct neurochemical pathways.
19. Known Adverse Effects
Include dysphoria, hallucinations, and psychotomimetic responses.
20. Severe Exposure Response
Seek emergency care for adverse reactions.
21. Solvent Use
Poorly soluble in water; soluble in organic solvents such as acetone and methanol.
22. Research Scheduling
Strict adherence to protocols essential.
23. Recommended Storage Duration
Long-lasting if stored properly.
24. Post-Research Stability
Maintain stability if stored correctly; dispose of expired substances safely.
25. Dependency or Sensitization Risk
Low addiction potential but strong psychological effects.
26. Long-Term Storage Recommendations
Store in sealed containers protected from light and humidity.
27. Alternative Research Compounds
Classical psychedelics such as LSD, psilocybin, and synthetic KOR agonists.

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